TABLE 2.
Normal Liver (n = 32) | Simple Steatosis (n = 19) | NASH (n = 25) | Pa | FDR | |
Total lipids in (mmol/l) | |||||
Chylomicrons and extremely large VLDL | 0.025 ± 0.021 | 0.036 ± 0.031 | 0.048 ± 0.026 | 0.0007 | 0.0065 |
Very large VLDL | 0.069 ± 0.050 | 0.090 ± 0.069 | 0.129 ± 0.061 | 0.0004 | 0.0065 |
Large VLDL | 0.277 ± 0.153 | 0.330 ± 0.211 | 0.456 ± 0.185 | 0.0017 | 0.0074 |
Medium VLDL | 0.566 ± 0.198 | 0.597 ± 0.266 | 0.783 ± 0.246 | 0.0022 | 0.0077 |
Small VLDL | 0.629 ± 0.145 | 0.596 ± 0.159 | 0.778 ± 0.205 | 0.0013 | 0.0065 |
Very small VLDL | 0.508 ± 0.124 | 0.462 ± 0.096 | 0.549 ± 0.172 | 0.1255 | 0.1515 |
Total IDL | 1.033 ± 0.255 | 0.936 ± 0.237 | 1.151 ± 0.344 | 0.0651 | 0.0872 |
Large LDL | 1.206 ± 0.301 | 1.095 ± 0.310 | 1.409 ± 0.416 | 0.0154 | 0.0250 |
Medium LDL | 0.694 ± 0.181 | 0.638 ± 0.203 | 0.844 ± 0.258 | 0.0095 | 0.0179 |
Small LDL | 0.457 ± 0.120 | 0.433 ± 0.156 | 0.574 ± 0.184 | 0.0097 | 0.0179 |
Very large HDL | 0.266 ± 0.135 | 0.267 ± 0.160 | 0.301 ± 0.193 | 0.6399 | 0.6399 |
Large HDL | 0.463 ± 0.264 | 0.390 ± 0.249 | 0.451 ± 0.300 | 0.3278 | 0.3585 |
Medium HDL | 0.844 ± 0.175 | 0.821 ± 0.107 | 0.901 ± 0.188 | 0.2808 | 0.3170 |
Small HDL | 1.110 ± 0.090 | 1.095 ± 0.168 | 1.167 ± 0.128 | 0.0781 | 0.0976 |
Total cholesterol in (mmol/l) | |||||
Large VLDL | 0.062 ± 0.035 | 0.071 ± 0.046 | 0.100 ± 0.040 | 0.0011 | 0.0065 |
Medium VLDL | 0.160 ± 0.053 | 0.159 ± 0.063 | 0.214 ± 0.066 | 0.0028 | 0.0082 |
Small VLDL | 0.232 ± 0.060 | 0.207 ± 0.054 | 0.277 ± 0.082 | 0.0028 | 0.0082 |
Total IDL | 0.633 ± 0.156 | 0.567 ± 0.148 | 0.703 ± 0.205 | 0.0440 | 0.0616 |
Large LDL | 0.797 ± 0.213 | 0.712 ± 0.222 | 0.937 ± 0.293 | 0.0157 | 0.0250 |
Medium LDL | 0.453 ± 0.131 | 0.406 ± 0.107 | 0.558 ± 0.188 | 0.0096 | 0.0179 |
Small LDL | 0.283 ± 0.083 | 0.260 ± 0.103 | 0.357 ± 0.127 | 0.0141 | 0.0247 |
Very large HDL | 0.151 ± 0.080 | 0.161 ± 0.095 | 0.175 ± 0.093 | 0.5106 | 0.5256 |
Large HDL | 0.217 ± 0.118 | 0.183 ± 0.130 | 0.208 ± 0.162 | 0.2098 | 0.2448 |
Medium HDL | 0.415 ± 0.094 | 0.401 ± 0.063 | 0.439 ± 0.098 | 0.3646 | 0.3867 |
Triglycerides in (mmol/l) | |||||
Chylomicrons and extremely large VLDL | 0.019 ± 0.015 | 0.027 ± 0.022 | 0.035 ± 0.019 | 0.0009 | 0.0065 |
Very large VLDL | 0.045 ± 0.032 | 0.060 ± 0.044 | 0.084 ± 0.040 | 0.0004 | 0.0065 |
Large VLDL | 0.163 ± 0.089 | 0.198 ± 0.125 | 0.269 ± 0.111 | 0.0019 | 0.0074 |
Medium VLDL | 0.292 ± 0.111 | 0.321 ± 0.156 | 0.415 ± 0.139 | 0.0035 | 0.0094 |
Small VLDL | 0.253 ± 0.067 | 0.255 ± 0.087 | 0.329 ± 0.088 | 0.0012 | 0.0065 |
Very small VLDL | 0.119 ± 0.028 | 0.112 ± 0.023 | 0.142 ± 0.040 | 0.0095 | 0.0179 |
Total IDL | 0.120 ± 0.032 | 0.111 ± 0.020 | 0.138 ± 0.041 | 0.0313 | 0.0457 |
Very large HDL | 0.010 ± 0.004 | 0.009 ± 0.004 | 0.013 ± 0.005 | 0.0079 | 0.0179 |
Small HDL | 0.042 ± 0.010 | 0.042 ± 0.010 | 0.048 ± 0.011 | 0.0673 | 0.0872 |
Apolipoproteins (g/l) | |||||
Apolipoprotein A-I | 1.367 ± 0.200 | 1.311 ± 0.186 | 1.476 ± 0.231 | 0.0179 | 0.0272 |
Apolipoprotein B | 0.860 ± 0.179 | 0.821 ± 0.189 | 1.023 ± 0.246 | 0.0060 | 0.0150 |
Kruskal-Wallis test. FDR with Benjamini-Hochberg method.