TABLE 3.

Effect of obesity surgery on NASH-related alterations in cholesterol concentration of different lipoproteins and serum total triglycerides in patients not using cholesterol lowering medication

	Not NASH (n = 27)	Possible/Definite NASH (n = 20)	Pb
Total cholesterol
Before	4.27 ± 0.9	4.98 ± 0.9	0.009
After	4.48 ± 1.0	4.43 ± 0.8	0.914
Change	4.9%	−11.0%	0.008
P value for changea	0.189	0.016
VLDL cholesterol
Before	0.76 ± 0.2	0.82 ± 0.2	0.237
After	0.69 ± 0.3	0.63 ± 0.2	0.813
Change	−9.2%	−23.2%	0.169
P value for changea	0.073	3.0 × 10−5
IDL cholesterol
Before	0.66 ± 0.2	0.78 ± 0.2	0.023
After	0.67 ± 0.2	0.64 ± 0.2	0.621
Change	1.5%	−17.9%	0.013
P value for changea	0.709	0.003
LDL cholesterol
Before	1.67 ± 0.5	2.04 ± 0.6	0.019
After	1.65 ± 0.6	1.57 ± 0.5	0.949
Change	−1.2%	−23.0%	0.022
P value for changea	0.752	0.001
HDL cholesterol
Before	1.18 ± 0.2	1.34 ± 0.3	0.037
After	1.48 ± 0.3	1.60 ± 0.3	0.085
Change	25.4%	19.4%	0.111
P value for changea	3.0 × 10−6	0.0002
Triglycerides
Before	1.60 ± 0.5	1.75 ± 0.5	0.143
After	1.25 ± 0.6	1.16 ± 0.4	0.966
Change	−21.9%	−33.7%	0.288
P value for changea	0.002	2.1 × 10−5

^aPaired samples t-test for within subjects comparison.

^bKruskall-Wallis independent samples test for between groups comparison.