Table 3.
Variant distribution of high grade serous ovarian carcinoma
| Sample ID/Gene | T1 | T2 | T3 | T4 | T5 | T6 | T7 | T8 | T9 |
|---|---|---|---|---|---|---|---|---|---|
| APC | - | **112175770G > A | **112175770G > A | *112175770G > A | *112175770G > A | *112175770G > A | *112175770G > A | **112175770G > A | *112175770G > A |
| EGFR | *55249063G > A | *55249063G > A | *55249063G > A | *55249063G > A | *55249063G > A | - | - | *55249063G > A | - |
| FGFR3 | **1807894G > A | **1807894G > A | **1807894G > A | **1807894G > A | **1807894G > A | **1807894G > A | **1807894G > A | **1807894G > A | **1807894G > A |
| KDR | *55972974T > A | *55972974T > A | *55972974T > A | - | **55972974T > A | **55972974T > A | *55972974T > A | *55972974T > A | *55972974T > A |
| KIT | *55593481A > G | - | - | *55593464A > C | - | - | - | - | - |
| MET | - | - | - | - | - | - | - | *116339672C > T | - |
| PDGFRA | **55141055A > G | **55141055A > G | **55141055A > G | **55141055A > G | **55141055A > G | **55141055A > G | **55141055A > G | **55152040C > T ** 55141055A > G | **55141055A > G |
| *55152040C > T | *55152040C > T | *55152040C > T | |||||||
| PIK3CA | - | - | - | - | - | *178952020C > T | - | - | - |
| RET | *43613843G > T | *43613843G > T | *43613843G > T | - | - | *43613843G > T | *43613843G > T | - | **43613843G > T |
| SMO | - | *128845088A > G | *128845088A > G | - | - | - | - | - | - |
| STK11 | - | - | - | *1223125C > G | - | *1223125C > G | - | - | - |
| TP53 | Deleterious* 7578406C > T | Deleterious* 7578271T > C | *7577035T > C Deleterious *7578190T > C | Deleterious* 7578442T > C | Deleterious* 7578190T > C | Deleterious* 7577094G > C | *7577035T > C | Deleterious* 7578406C > T | Deleterious* 7577581A > G |
| # Altered genes | 7 | 8 | 8 | 7 | 6 | 8 | 6 | 7 | 6 |
| # Del variant | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 |
| # Total variants | 8 | 8 | 10 | 7 | 6 | 9 | 6 | 8 | 6 |
**Homozygous.
*Heterozygous.
Del = Deleterious.