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. 2014 Nov 18;15(1):978. doi: 10.1186/1471-2164-15-978

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© Shao et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Distribution of DNA methylation level and entropy for three methylomes. The distribution was calculated based on the 754,372 common segments of all three methylomes. (A) DNA methylation level. (B) DNA methylation entropy. The DNA methylation level was plotted against the DNA methylation entropy for all three cell-types: ADS (C), ADS-adipose (D), and ADS-iPSCs (E). The distribution of the median of the methylation entropies for simulated segments with 4 CpG sites was plotted (F).