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. 2014 Nov 24;9(11):e113690. doi: 10.1371/journal.pone.0113690

Figure 2. Topical application of Stattic accelerates vaccinia disease.

Figure 2

A) Schedule of SCID mouse experiments, in which Stattic or DMSO was applied topically for one week before and after ACAM-2000 scarification. B) Weight loss in ACAM-2000 infected SCID mice treated with STAT3 inhibitor stattic or vehicle control. Mean of 9–10 mice is shown. C) Survival proportions in ACAM-2000 infected SCID mice treated with STAT3 inhibitor stattic or vehicle control (n = 9–10 per group). Asterisk, p≤0.05. Representative of three experiments is shown.