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. Author manuscript; available in PMC: 2014 Nov 24.
Published in final edited form as: Science. 2014 Sep 5;345(6201):1188–1191. doi: 10.1126/science.1255030

Figure 4. The acceptor end of ap/ap tRNA simultaneously contacts the A and P loops of 23S rRNA.

Figure 4

During translocation, the 3′ acceptor end of peptidyl-tRNA moves from the (A) classical A/A state to the (B) intermediate ap/ap state to the (C) classical P/P states, facilitated by conformational changes in the A and P loops.