Table 1.

Properties of anesthetics

Anesthetic	MAC at 25°C	cLogP	Membrane concentration (at 1 MAC)	Mole fraction (at 1 MAC)
	mM		mM
1,2-DFB	0.70	2.2	106	0.087
1,4-DFB	0.59	2.4	135	0.109
1,3,5-TFB	0.60	2.5	174	0.136
HFB	0.25	2.4	57	0.049
ISO	0.30	2.3	57	0.049

MAC values from Solt et al. (2006); cLogP values were estimated using the ACD/Labs LogP algorithm on ChemSpider. Concentrations and mole fractions were calculated as described in Materials and methods.