Table 3.

Anesthetic effects on the voltage dependence of Na_v inactivation

Anesthetic	V1/2 control	V1/2 drug	V1/2 wash	ΔV1/2	n
1,2-DFB	−71.7 ± 2.8	−81.1 ± 3.0a	−77.1 ± 3.6b	−9.4 ± 0.9	6
1,4-DFB	−69.5 ± 5.6	−78.5 ± 5.4a	−74.6 ± 5.6a	−9.0 ± 1.0	6
1,3,5-TFB	−69.2 ± 5.4	−76.5 ± 5.8a	−73.3 ± 5.9b	−7.4 ± 1.0	5
HFB	−69.6 ± 4.9	−74.3 ± 4.8b	−72.2 ± 5.0c	−4.8 ± 0.7	5
ISO	−68.8 ± 4.2	−73.4 ± 4.3a	−71.6 ± 3.3b	−4.7 ± 0.9	6

^aP < 0.0001 versus control by two-tailed paired Student’s t test.

^bP < 0.001 versus control by two-tailed paired Student’s t test.

^cP < 0.01 versus control by two-tailed paired Student’s t test.