Table 1.
Cytotoxicity results (IC50 ± SD, µM) of compounds 4a-4f against cancerous cell lines

| Compounds | R | SKNMC | HEP-G2 | MCF-7 |
|---|---|---|---|---|
| 4a | o-NO2 | 16.2±1.001 | 12.7±0.023 | >25 |
| 4b | m-NO2 | 15.3±1.12 | 18.5±1.04 | >25 |
| 4c | p-NO2 | 10.8±0.08 | 14.1±1.52 | >25 |
| 4d | m-Cl | 25.1±0.71 | 11.6±0.12 | >25 |
| 4e | p-Cl | 17.8±1.42 | 22.3±1.89 | >25 |
| 4f | p-F | 16.2±0.005 | 14.7±1.004 | >25 |
| Doxorubicin | - | 5.7±0.02 | 5.8±1.01 | 8.7±0.15 |