Figure 2.

Demyelination of the lumbar spinal cords in mice induced with experimental autoimmune encephalomyelitis and treated with genistein (300 mg/kg) or DMSO. LFB/Cresyl violet staining was applied to assess spinal cord demyelination. A-1 and A-2 demonstrate demyelination in the mice receiving DMSO (A-1) or genistein (A-2) from the onset of disease for 10 days. A-3 and A-4 are the spinal cord sections of the mice that received DMSO (A-3) or genistein (A-4) from day 30 post induction for 10 days. Blue areas represent myelin