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. 2014 Sep 19;53(12):1137–1147. doi: 10.1007/s40262-014-0173-y

Fig. 4.

Fig. 4

Elosulfase alfa exposure and percent change in uKS over 24 weeks. Pharmacokinetic values are from week 22. Percent change of uKS is the percent change in creatinine-normalized uKS levels between baseline and week 24. AUC last area under the plasma concentration-time curve from time zero to the time of last measurable concentration, C max observed maximum plasma concentration, qow every other week, uKS urinary keratan sulfate