Table 2.
Multivariable analysis of the effects of demographic factors on rates of multiple drug intolerance
| Factor | Odds ratio (95 % CI) | p value |
|---|---|---|
| Age (years) | 0.716 | |
| <45 | – | – |
| 45–64 | 1.02 (0.86–1.22) | 0.789 |
| 65+ | 1.07 (0.90–1.27) | 0.436 |
| Weight (kg) | 0.364 | |
| <50 | 1.04 (0.82–1.34) | 0.731 |
| 50–85 | – | – |
| >85 | 0.90 (0.77–1.05) | 0.185 |
| Deprivation score | 0.646 | |
| <0.1 | – | – |
| 0.1–0.3 | 0.96 (0.83–1.12) | 0.634 |
| >0.3 | 0.92 (0.76–1.10) | 0.350 |
| Sex | <0.001* | |
| Female | 2.06 (1.77–2.40) | <0.001* |
| Male | – | – |
| Ethnicity | 0.133 | |
| White | – | – |
| Asian | 0.87 (0.66–1.13) | 0.295 |
| Black | 0.76 (0.51–1.13) | 0.174 |
| Mixed | 1.11 (0.60–2.07) | 0.736 |
| Other | 0.66 (0.35–1.26) | 0.209 |
| Unspecified | 0.62 (0.40–0.97) | 0.035 |
| Comorbidities | <0.001* | |
| None | – | – |
| 1 | 1.26 (1.05–1.52) | 0.012* |
| 2 or more | 1.91 (1.64–2.22) | <0.001* |
| Admissions prior to first allergy | <0.001* | |
| No | – | – |
| Yes | 1.59 (1.30–1.94) | <0.001* |
Results from a multivariable binary logistic regression
* Significant at p < 0.05