Skip to main content
. Author manuscript; available in PMC: 2015 Oct 23.
Published in final edited form as: Cell. 2014 Oct 23;159(3):543–557. doi: 10.1016/j.cell.2014.09.033

Fig 6. Bptf is required for OR expression and enhancer interactions.

Fig 6

A. Olfr1507 IF (green) in Foxg1-Cre; Bptf flox/+ (heterozygote) and Foxg1-Cre; Bptf flox/flox (KO) MOE at e18.5. DAPI is the nuclear stain (blue).

B. PanOR RNA ISH in Bptf heterozygote and KO.

C-E. ISH for developmental markers in Bptf het (top) and KO (bottom).

F. Adcy3 IF (red) and Vglut2 IF (green) in Bptf het (top) and KO (bottom). DAPI (blue) is nuclear stain.

G. Quantification of OR ISH experiment (panel B) in Bptf het and KO. Error bars represent the variance over duplicate experiments.

H. Quantification of DNA FISH co-localizations between H and Sfaktiria BAC probes and between H and Lipsi BAC probes in Bptf het and KO. The Y-axis is percent OSN and sustentacular cell nuclei containing co-localized probes.

I. DNA FISH with complex pan olfactory receptor (PanOR) probe (red) in Bptf het and KO OSNs. DAPI is nuclear stain (blue).