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. Author manuscript; available in PMC: 2015 Nov 6.
Published in final edited form as: Cell. 2014 Nov 6;159(4):751–765. doi: 10.1016/j.cell.2014.09.056

Figure 2. The calcium activity pattern of AIY correlates with locomotion speed and direction-switch in freely-behaving worms.

Figure 2

(A) Calcium and locomotion velocity traces acquired with the CARIBN system. The windows highlighted in green denote reversals.

(B–C) Cross-correlation analysis shows that AIY calcium activity correlates with forward but not backward locomotion speed. The shades along the curves represent error bars (SEM). n=8.

(D) Cross-correlogram showing that reversal initiation correlates with AIY activity decrease. Since reversal initiation occurs in an all-or-none fashion, cross-correlogram was used to analyze correlation using a method similar to that reported previously (Brown et al., 2004). The occurrence of a reversal event and the decrease/increase in calcium level at a given time point were analyzed for correlation. A negative value indicates that a reversal event coincided with a decrease in calcium level, and vice versa.

Also see Figure S2 and Supplemental Movie 1.