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. Author manuscript; available in PMC: 2015 Nov 6.
Published in final edited form as: Cell. 2014 Nov 6;159(4):751–765. doi: 10.1016/j.cell.2014.09.056

Figure 6. UNC-29/ACR-16 and ACC-2 are required for ACh-gated cation and Cl− current in RIB and AIZ, respectively.

Figure 6

(A–B) Patch-clamp recording shows that ACh evokes a cation current in RIB. (A) Sample traces. (B) I-V relationship. n ≥7.

(C–D) ACh-gated current in RIB requires UNC-29 and ACR-16. Voltage: -60 mV. (C) Sample traces. (D) Bar graph. n=6. **p<0.002 (t test).

(E–F) Patch-clamp recording shows that ACh evokes a Cl− current in AIZ. Shown in (E) are sample traces. (F) I–V relationship. Low Cl−: 25 mM. High Cl−: 140 mM. n ≥5.

(G–H) ACh-gated Cl− current requires ACC-2. Voltage: −60 mV. (G) Sample traces. (H) Bar graph. n ≥6. **p<0.009 (t test).

All error bars: SEM. ACh: 1 mM.