Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Nov 27;6(11):776–782. doi: 10.4254/wjh.v6.i11.776

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

©2014 Baishideng Publishing Group Inc. All rights reserved.

PMC Copyright notice

The PI3K/AKT/mTOR pathway. IRS1: Insulin receptor subsrate 1; PI3K: Phophoinositide-3-kinase; PIP-2: Phosphatidylinositol (4,5)-biphosphate; PIP-3: Phosphatidylinositol (3,4,5)-triphosphate; PTEN: Phosphatase and tensin homologue on chromosome 10 gene; PDK1: Phosphoinositide-dependent protein kinase-1; PKB/AKT: Serine/threonine protein kinase; TSC1-TSC2: Tuberous sclerosis 1-tuberous sclerosis 2 complex; 4EBP1: Eukaryotic initiation factor 4E binding protein 1; eIF4E: Eukaryotic initiation factor 4E; S6K1: 70S ribosomal protein S6 kinase; SFKs: SRC family kinases.