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. Author manuscript; available in PMC: 2014 Nov 25.
Published in final edited form as: Dev Neurosci. 2013 Sep 7;35(5):384–395. doi: 10.1159/000351026

Fig. 5.

Fig. 5

Effect of age and SKF 83959 on p75NTR expression in NAc, CP and PFC of adult and juvenile rats. (a, b) There were no age-related or SKF 83959-induced alterations in p75NTR expression in NAc or CP. (c) In PFC, basal expression of p75NTR did not differ between age groups. However, SKF 83959 (1.5 mg/kg) induced a significant increase in p75NTR levels in both adult and juvenile rats. Representative blots for each region are also shown. GAPDH was used as a loading control. Data are represented as mean ± SEM, and are expressed as a percent of adult/saline controls. {NAc: Drug, F(1,22)=2.0, P=0.18, n.s.; Age, F(1,22)=0.5, P=0.48, n.s.; Drug × Age, F(1,22)=0.9, P=0.36, n.s.; CP: Drug, F(1,21)=2.6, P=0.11, n.s.; Age, F(1,21)=0.30, P=0.59, n.s.; Drug × Age, F(1,21)=0.9, P=0.35, n.s.; PFC: Drug, F(1,22)=13.0, P=0.002; Age, F(1,22)=2.7, P=0.11, n.s.; Drug × Age, F(1,22)=0.59, P=0.45, n.s.}. N=6-7/group per experiment. #P<0.05 compared to saline controls of the same age.