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. Author manuscript; available in PMC: 2015 Dec 14.
Published in final edited form as: Polyhedron. 2014 Dec 14;84:150–159. doi: 10.1016/j.poly.2014.07.005

Figure 11.

Figure 11

Single electrode versus two electrode readout of a surface patterned with two strips of well matched DNA and two strips that contain a single-base mismatch. (a) Electrochemical readout from a single electrode. The characteristic CV shape of the electrocatalytic process between MB and ferricyanide is evident. (b) Two-electrode electrocatalysis in which a probe microelectrode reduces electrochemically-produced ferrocyanide back to ferricyanide, which no longer limits electrocatalysis by both the amount of electron sink and its speed of diffusion. Additionally, there is differentiation between the two different sequences of DNA: matched (black arrows) and mismatched (red arrows).