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. 2014 Nov 19;15:120. doi: 10.1186/s12868-014-0120-8

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© Kostyalik et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Illustrations of Markov chains during the onset and steady phase. Numeric data represent the relative mean values of sojourn times and transition rates in the treatment groups compared to the mean values of the HC-VEH group (sojourn times and transition rates of the HC-VEH group are 1). The size of circles aligns the changes in sojourn times. Thick, uninterrupted arrows represent significant increase, dashed arrows show significant decrease and slight arrows sign no significant changes in transition speed compared to the HC-VEH group. Significant alterations are highlighted in bold, underlined characters.