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. 2014 Nov 19;15:120. doi: 10.1186/s12868-014-0120-8

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© Kostyalik et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Aggregated REM sleep measures calculated by standard sleep analysis in the summarized first 2 h of passive phase. Changes in the A) amount, B) episode number, C) episode duration and D) the latency time of REM sleep. Data are presented as mean ± SEM of 6–7 animals per group. *p < 0.05 means significant post hoc effects of RD-VEH group compared to the HC-VEH group; ^# p < 0.05 and ^## p < 0.01 mean significant post hoc effects of and RD-SSRI group compared to HC-SSRI group. Groups: home cage-chronic vehicle treatment (HC-VEH); home cage-chronic escitalopram treatment (HC-SSRI); REM sleep deprivation-chronic vehicle treatment (RD-VEH); REM sleep deprivation-chronic escitalopram treatment (RD-SSRI).