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. 2014 Nov 19;9:114. doi: 10.1186/s13018-014-0114-3

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© Kankilic et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Histological images (A-E). PLLA/β-TCP without IRO group had a mild tissue reaction in (A) week 1 with HE (B) and week 6 with MT. The implant is degrading but still present at 6 weeks. PLLA/β-TCP with IRO group had evident bone damage and granulation tissue formation with mononuclear cell infiltration and periosteal reaction in (C) week 1 with MT and (D) week 6 with HE, respectively. V-PLLA/β-TCP had better morphologic features of the bone and marrow in (E) week 1 with HE with the presence of new forming healthy spongy bone. CT connective tissue, TB trabecular bone, CB compact bone, BM bone marrow, GT granulation tissue, I implant, HE hematoxylin and eosin, MT Masson’s trichrome.