Table 1.

Concentration and activity in maternal plasma of coagulating and anticoagulating factors and their relation with thrombin generation in the great obstetrical syndromes.

	TF concentration and/or activity	TFPI concentration and/or activity	TAT III complexes concentration	Protein Z concentration	Thrombin generation	References
Premature rupture of membranes	Activity ↑ Concentration ↑	Concentration ↓	Concentration ↑	Concentration ↓	↑	(Erez et al., 2010; Erez et al., 2009; Kusanovic et al., 2007; Gris et al., 2002; Paidas et al., 2005)
Preterm labor	Activity ↑ Concentration =	Activity = Concentration ↓	Concentration ↑	Concentration ↓	↑	(Erez et al., 2010; Erez et al., 2009; Kusanovic et al., 2007; Gris et al., 2002; Paidas et al., 2005)
Fetal demise	Activity = Concentration =	Activity = Concentration ↓	Concentration ↑	Concentration ↓	↑	(Erez et al., 2010; Erez et al., 2009; Kusanovic et al., 2007; Gris et al., 2002; Paidas et al., 2005)
Preeclampsia	Activity ↑ Concentration ↑	Concentration ↑	Concentration ↑	Concentration ↓	↑	(Erez et al., 2010; Erez et al., 2009; Kusanovic et al., 2007; Gris et al., 2002; Paidas et al., 2005)
Intrauterine growth retardation/small for gestational age	Activity ↑ Concentration ↓	Concentration =	Concentration ↑	Concentration ↓	↑	(Erez et al., 2010; Erez et al., 2009; Kusanovic et al., 2007; Gris et al., 2002; Paidas et al., 2005)