Figure 2.

Pre- and postbaseline HbA_1c in the complete cohort. (A) Distribution of prebaseline HbA_1c in 279 patients with CKD stages 1–3 from the Joslin Proteinuria Cohort. The black contour outlines distribution of HbA_1c (5-year average) in 1412 patients from the Joslin Clinic without proteinuria. (B) Distribution of changes between pre- and postbaseline HbA_1c (postbaseline level measured over median of 5.1 years). Improvements >1 percentage point are light gray, deteriorations >1 percentage point are dark gray, and changes within a 1% boundary are depicted in intermediate shade.