Table 2.
Enhanced release of cytokines in AQP4 −/− mice than in AQP4 +/+ mice following intracerebral hemorrhage
| Mouse cytokine antibody array | Fold increase | |
|---|---|---|
| IL-1β | Interleukin-1 β | 2.1 |
| TNFα | Tumor necrosis factor α | 2.3 |
| IL-6 | Interleukin-6 | 1.65 |
| IL-12 | Interleukin-12 | 1.62 |
| bFGF | Basic fibroblast growth factor | −2.2 |
| VEGFRI | Vascular endothelial growth factor receptor 1 | −1.8 |
| DPPIV/CD26 | Dipeptidyl peptidase IV | −1.72 |
| Dtk | Dtk | −1.76 |
| E-seletin | Endothelial leukocyte adhesion molecule-1 | −1.65 |
| FcγR II B | Human immune globulin Fc receptor | −1.82 |
| GITR | Glucocorticoid induced tumor necrosis factor receptor | −1.68 |
| TSLP | Human thymic stromal lymphopoietin | −1.74 |
Quantitative analysis of the release of 12 cytokines 3 days after intracerebral hemorrhage. Values are means of two independent experiments, statistically different between AQP4−/− and AQP4+/+ mice.