Table 2.

List of mutations in pfmrp of Plasmodium falciparum along with properties of both substituent and substituted amino acids.

Site of mutation	Substituted amino acids	Side chain polarity	Side chain charge	Hydrophobicity index	Substituent amino acid	Side chain polarity	Side chain charge	Hydrophobicity index
191	Tyrosine	Polar	Neutral	−1.3	Histidine	Basic polar	Partially positive	−3.2
437	Alanine	Non polar	Neutral	1.8	Serine	Polar	Neutral	−0.8