Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Composition of gemcitabine and gemcitabine prodrugs in Caco-2 cell uptake studies without Gly-Pro (mean ± SD, n = 3).
| Compound | Cytosine (%) | Gemcitabine (%) | Prodrug (%) |
|---|---|---|---|
| Gemcitabine | 50 | 50 | |
| 5′-L-Phenylalanyl- gemcitabine | 0 | 18 | 82 |
| 5′-D-Phenylalanyl- gemcitabine | 0 | 31 | 69 |
| 5′-L-Valyl-gemcitabine | 0 | 15 | 85 |
| 5′-D-Valyl-gemcitabine | 0 | 10 | 90 |
