Table 2.

Summary of baseline and post-intervention systemic sex steroid hormones and estrogen metabolites (n = 34)

Sex steroid hormones	Baseline	Post-intervention	% change	P b
Estradiol, pg/ml	12.3 ± 20.7a	15.5 ± 34.9	22.4 ± 178	0.47
Estrone, pg/ml	26.1 ± 12.7	25.8 ± 14.3	1.4 ± 38.3	0.83
Testosterone, ng/ml	0.18 ± 0.11	0.18 ± 0.12	−0.85 ± 27.2	0.86
SHBG, nmol/L	42.1 ± 17.6	45.3 ± 18.0	10.0 ± 17.8	<0.01
2-OHE1, ng/mg creatinine	9.5 ± 8.8	13.8 ± 8.75	73.2 ± 132	<0.01
16α-OHE1, ng/mg creatinine	6.6 ± 6.1	6.6 ± 3.0	15.9 ± 51.0	0.08
2-OHE1/16α-OHE1 ratio	1.7 ± 1.4	2.7 ± 2.7	84.5 ± 175	<0.01

^aData are presented as mean ± SD.

^bDerived from a paired t-test for % change from baseline to post-intervention.