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. 2014 Oct 27;15(Suppl 7):S5. doi: 10.1186/1471-2164-15-S7-S5

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Copyright © 2014 Costa et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Topology of the HIV-1 protease. Topology of HIV-1 protease colored according to the convention proposed in Perryman et al, 2003. In red the flap domain (residues 43-58); in cyan the ears (35-42); in green the cheek turns (11-22); in yellow the cheek sheets (59-75); in blue the eyes (23-30); in magenta the nose (6-10) and in orange the whiskers (1-5 and 95-99). The 36^thresidue is represented by a grey sphere.