Table 1.

Characteristics of patients with asthma

	All patients (No. 63)	Patients with R5-R20 ≤ 0.03 kPa s l −1 (No. 33)	Patients with R5-R20 > 0.03 kPa s l −1 (No. 30)
Age (years)	42 ± 14	38 ± 12	45 ± 15*
Sex (F/M)	36/27	13/20	23/7**
BMI (kg/m2)	24 ± 3	23 ± 2	25 ± 3
Atopy (Y/N)	52/11	31/2	21/9*
Smoking (Y/N)	12/51	9/24	4/26
ICS use (Y/N)	29/34	14/19	15/15
ICS dose (μg/day)#	701 ± 540	779 ± 598	628 ± 490
ACT > 20/ACT ≤ 19	49/14	29/4	20/10*
FEV1 (% of pred)	92 ± 14	94 ± 13	90 ± 15
FVC (% of pred)	99 ± 13	102 ± 12	97 ± 13
FEV1/SVC (%)	75 ± 8	75 ± 6	75 ± 9
FEF25–75 (% pred)	76 ± 25	77 ± 21	74 ± 29
R5-R20 (kPa s l−1)	0.057 ± 0.072	0.011 ± 0.014	0.108 ± 0.076**
X5 (kPa s l-1)	−0.134 ± 0.07	−0.098 ± 0.02	−0.172 ± 0.09**
PD20 (μg)	181 (132–249)	207 (134–322)	156 (96–254)
DRS (%/μg)	0.103 (0.074-0.143)	0.086 (0.054-0.135)	0.125 (0.076-0.205)
∆FVC%	13.6 ± 5.1	11.5 ± 4.8	15.8 ± 4.6**

Values are expressed as mean ± SD, ratio or geometric mean (Confidence Intervals).

^#only in patients using ICS; *p < 0.05; **p < 0.01.