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. 2014 Nov 1;9:225. doi: 10.1186/s13014-014-0225-3

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© Zou et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Histogram representations of the motion effect. a) and b) Inter-fraction interplay effect: the voxel histogram of the largest dose differences in PTV volume and GTV volume among all four fractions for three patients; c) and d) difference in cumulative 4D dose with and without motion: histogram of dose differences in the PTV and GTV due to motion. The bars represent the percentage of the voxels in the PTV or GTV with dose differences in 0.2 Gy bins.