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. Author manuscript; available in PMC: 2014 Nov 25.
Published in final edited form as: J Urol. 2012 Nov 15;189(5):1656–1661. doi: 10.1016/j.juro.2012.11.084

Table 2.

Surgery and chemotherapy outcomes in 31 patients with predominant plasmacytoid histology

No. Pts (%)
Surgery type:
  No surgery 9 (29)
  Cystectomy/cystoprostatectomy 17 (55)
  Exenteration 2 (6)
  Transurethral bladder tumor resection 2 (6)
  Surgery aborted due to T4b stage 3 (10)
  Unknown 1 (3)
Lymph node dissection:
  Yes 20 (65)
  No 9 (29)
  Unknown 2 (6)
Lymph node status at surgery:
  Pos 11 (35)
  Neg 9 (29)
  Not applicable (no surgery or no lymph node dissection) 10 (32)
  Unknown 1 (3)
Margin status at surgery:
  Pos 2 (6)
  Neg 18 (58)
  Not applicable (no surgery or unreported margins) 10 (32)
  Unknown 1 (3)
Pathological CR:
  Yes 4 (13)
  No 17 (55)
  Not applicable (no or aborted surgery) 9 (29)
  Unknown 1 (3)
Chemotherapy setting:
  None 3 (10)
  Neoadjuvant 7 (23)
  Adjuvant 7 (23)
  Metastatic 14 (45)
Best chemotherapy response:
  CR (tumor resolution on imaging) 6 (19)
  Less than CR on imaging 10 (32)
  Stable disease 1 (3)
  Progressive disease 1 (3)
  Unknown 2 (6)
  Not applicable (adjuvant or no chemotherapy) 11 (35)
Chemotherapy type:*
  Dose dense MVAC 14 (45)
  Ifosfamide, doxorubicin + gemcitabine 8 (26)
  GC based 6 (19)
  Other 6 (19)
  Unknown 1 (3)
  None 3 (10)
Post-chemotherapy progression site:
  Peritoneum 19 (61)
  Retroperitoneal lymph nodes 3 (10)
  Bladder 3 (10)
  Bone, lungs, scrotum 3 (10)
  Unknown 3 (10)
  No progression 5 (16)
*

CR plus partial response in 7 of 9 patients with dose dense MVAC, 6 of 7 (86%) with ifosfamide, doxorubicin and gemcitabine, all 5 (100%) with GC based chemotherapy and 3 of 4 (75%) with other chemotherapy, not including those with adjuvant chemotherapy or missing response data and with percents totaling greater than 100% since some patients received more than 1 regimen.

Some patients had progression at different sites.