Table 4.

Summary of telaprevir pharmacokinetic parameters^*

Pharmacokinetic parameters	Cohort 2 dolutegravir + telaprevir (n = 15)	Telaprevir alone§
AUC0–τ (μg h ml−1)	19.2 (19)	22.3
Cmax (μg ml−1)	3.21 (17)	3.51
Cτ (μg ml−1)	1.75 (26)	–
Cmin (μg ml−1)	1.72 (25)	2.03
t1/2 (h)†	5.14 (27)	–
Tmax (h)‡	3.00 (2.0, 4.0)	–

Abbreviations are as for Table 3.

^*Geometric mean (between subject coefficient of variation, %CVb).

^†n = 10.

^‡Presented as median (range).

^§Telaprevir package insert, 2013.