Figure 3.

Calculated 25(OH)D concentrations (solid line) and 90% CI (dashed lines) vs. time according to a 100 000 IU per 3 months dosing scheme in patients with baseline concentration <10 ng ml⁻¹ (A), a 100 000 IU per 3 months dosing scheme in patients with baseline concentrations between 10 and 30 ng ml⁻¹ (B) and an intensive (100 000 IU per 2 weeks, two times) and a maintenance dosing scheme (after 2 weeks, 100 000 IU per 3 months) in patients with baseline concentrations <10 ng ml⁻¹ (C). The horizontal lines represent the 30 and 80 ng ml⁻¹ 25(OH)D targets for efficacy and toxicity, respectively