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Pharmacokinetic parameters of HM30181 by dose
| Dose (mg) | n | tmax (h) | Cmax (μg l−1) | AUC(0,tlast) (μg l−1 h) |
|---|---|---|---|---|
| 15 | 6 | 12.0 [8, 24] | 2.06 ± 0.94 | 105.26 ± 46.59 |
| 60 | 6 | 30.0 [8, 74.8] | 2.37 ± 0.88 | 157.73 ± 56.99 |
| 180 | 6 | 24.0 [8, 107.8] | 4.85 ± 2.6 | 292.83 ± 41.7 |
| All | 18 | 24.0 [8, 107.8] | 3.10 ± 2.03 | 185.27 ± 93.36 |
Data are mean ± SD except for tmax, for which median [min, max] is shown.
