Table 1.
Presentations, admissions and use of NAC across three UK hospitals
| Pre | Post | Change | |||
|---|---|---|---|---|---|
| +/− | 95% CI | P | |||
| Presentations (n) | |||||
| Centre 1 | 990 | 1111 | 12.2% | 3.0, 22.3 | 0.008 |
| Centre 2 | 378 | 386 | 2.1% | −11.4, 17.6 | 0.772 |
| Centre 3 | 335 | 357 | 6.6% | −8.2, 23.7 | 0.403 |
| Overall | 1703 | 1854 | 8.9% | 1.9, 16.2 | 0.01 |
| Admitted (%) | |||||
| Centre 1 | 54.7 (541/990) | 63.1 (701/1111) | 8.5% | 4.2, 12.7 | <0.001 |
| Centre 2 | 79.1 (299/378) | 86.8 (335/386) | 7.7% | 2.4, 13.0 | 0.005 |
| Centre 3 | 65.7 (220/335) | 69.8 (249/357) | 4.1% | −2.9, 11.0 | 0.251 |
| Overall | 62.2 (1060/1703) | 69.3 (1285/1854) | 7.1% | 4.0, 10.2 | <0.001 |
| Treated with NAC (%) | |||||
| Centre 1 | 39.0 (386/990) | 49.6 (551/1111) | 10.6% | 6.4, 14.8 | <0.001 |
| Centre 2 | 30.4 (115/378) | 50.3 (194/386) | 19.8% | 13, 26.7 | <0.001 |
| Centre 3 | 37.3 (125/335) | 50.7 (181/357) | 13.4% | 6.2, 20.7 | <0.001 |
| Overall | 36.8 (626/1703) | 50 (926/1854) | 13.2% | 10.0, 16.4 | <0.001 |
Centre 1 = Royal Infirmary of Edinburgh; centre 2 = Guy’s and St Thomas’ NHS Foundation Trust, London; centre 3 = Royal Victoria Infirmary, Newcastle upon Tyne.