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. Author manuscript; available in PMC: 2015 Jan 15.
Published in final edited form as: Bioorg Med Chem. 2013 Nov 8;22(2):917–926. doi: 10.1016/j.bmc.2013.10.051

Figure 1.

Figure 1

Alpha helical proteomimetic. Adapted from Williams et. al.11 A) Coactivator NR Box forms an α-helix with an LXXLL motif. B) 4,4′-Biphenyl scaffold. C) Target compounds 1a–m with varying substitution (see Table 1)