Table 2.
Summary of genes expressed preferentially in TCs, as compared with others
Compared pairs/fold down-regulated | >0 | >1 | >4 | ||||
---|---|---|---|---|---|---|---|
TC5 versus others | 140 | 14 | 0 | ||||
TC10 versus others | 236 | 38 | 0 | ||||
TCs versus others | 80 | 6 | 0 | ||||
Gene symbol | Folds (TC5 versus others/TC10 versus others) | ||||||
Fibroblast | Stem | ATII | CD8_T_BL | CD8_T_LL | Basal_cell | Duct_cell | |
(A) Genes down-regulated between 0-and 1-folds in TCs as compared with others | |||||||
1500012F01Rik | 1.00/2.24 | 2.51/4.68 | 0.09/0.29 | 0.83/1.11 | 1.30/1.68 | 2.50/3.01 | 4.17/4.95 |
1600027N09Rik | 0.02/0.26 | 0.24/0.53 | 3.26/2.85 | 5.59/4.77 | 6.52/5.68 | 6.23/5.32 | 6.80/5.85 |
1700058C13Rik | 0.01/0.29 | 0.03/0.31 | 6.00/5.54 | 6.63/5.93 | 15.2/13.91 | 7.23/6.46 | 4.82/4.30 |
2010317E24Rik | 0.71/2.34 | 1.58/4.04 | 0.03/0.47 | 0.23/0.70 | 1.38/2.34 | 10.45/14.81 | 10.14/14.46 |
2810408M09Rik | 1.13/1.13 | 0.66/0.66 | 20.58/14.77 | 1.23/0.58 | 14.91/10.44 | 65.85/46.34 | 29.46/20.69 |
4921504E06Rik | 0.16/0.37 | 0.31/0.55 | 6.25/5.27 | 0.87/0.57 | 8.86/7.40 | 11.6/9.56 | 9.10/7.51 |
6820408C15Rik | 0.02/0.06 | 0.54/0.61 | 99.87/75.87 | 8.76/6.22 | 28.01/20.77 | 26.11/19.03 | 17.2/12.51 |
Abca2 | 0.77/1.04 | 0.51/0.73 | 11.84/9.81 | 5.21/4.07 | 6.05/4.84 | 8.82/7.01 | 6.99/5.55 |
Acvr2a | 1.31/1.33 | 0.42/0.43 | 23.28/16.86 | 13.98/9.7 | 25.29/18.05 | 84.04/59.65 | 70.93/50.56 |
Angptl2 | 0.52/0.45 | 1.97/0.31 | 16.78/0.65 | 9.96/1.22 | 5.33/2.03 | 14.94/3.34 | 20.00/1.38 |
Api5 | 0.06/0.28 | 0.40/1.50 | 3.39/9.94 | 6.09/5.56 | 4.92/2.84 | 3.10/8.51 | 3.11/11.60 |
Arhgap1 | 0.30/0.39 | 0.05/0.84 | 1.45/3.21 | 1.27/5.61 | 0.44/4.59 | 4.67/2.81 | 3.64/2.84 |
Arpc5l | 1.84/1.17 | 0.11/0.75 | 1.81/1.99 | 9.73/1.70 | 7.56/0.73 | 9.55/5.73 | 5.43/4.53 |
Atf2 | 0.15/2.57 | 0.26/0.39 | 2.39/1.58 | 7.92/8.55 | 3.92/6.73 | 8.87/8.38 | 5.91/4.74 |
B2m | 1.13/0.44 | 0.57/1.06 | 2.50/1.63 | 4.18/3.06 | 4.50/2.19 | 2.32/1.70 | 1.22/1.32 |
Catsper2 | 1.51/0.83 | 0.31/1.01 | 14.79/2.94 | 24.41/9.06 | 27.92/4.63 | 19.7/10.11 | 15.59/6.82 |
Cbfa2t2 | 0.21/0.82 | 0.43/0.34 | 0.27/1.18 | 0.97/2.13 | 0.86/2.37 | 0.60/1.00 | 0.28/0.35 |
Cdca7 | 1.89/1.49 | 6.28/0.30 | 1.05/10.46 | 1.2/16.91 | 0.10/19.66 | 2.18/13.55 | 2.49/10.73 |
Cep110 | 1.61/0.62 | 0.28/0.92 | 0.84/0.24 | 7.14/0.87 | 4.90/0.79 | 5.53/0.51 | 2.91/0.22 |
Chchd5 | 0.45/3.93 | 0.13/11.43 | 6.34/1.55 | 3.16/1.67 | 2.13/0.35 | 12.54/2.84 | 10.66/3.24 |
Ciz1 | 0.30/2.69 | 0.21/0.81 | 1.53/0.90 | 0.84/7.16 | 0.68/4.99 | 7.8/5.53 | 4.74/2.93 |
Cry2 | 0.11/1.18 | 0.15/0.69 | 13.7/7.05 | 4.83/3.43 | 2.42/2.38 | 10.9/13.38 | 11.47/11.46 |
Ddx27 | 0.42/0.74 | 0.44/0.62 | 0.20/1.47 | 1.27/0.74 | 1.09/0.61 | 5.47/7.32 | 6.52/4.46 |
Ddx31 | 0.31/0.36 | 0.93/0.91 | 0.51/2.65 | 1.79/8.07 | 0.75/9.21 | 5.42/17.28 | 5.09/13.41 |
Depdc7 | 1.34/0.33 | 0.42/0.38 | 13.2/11.89 | 0.67/3.96 | 2.85/1.96 | 2.96/9.11 | 33.03/9.65 |
Dsn1 | 0.61/0.26 | 1.33/0.31 | 6.39/6.62 | 39.29/12.48 | 47.16/10.54 | 12.99/6.54 | 23.88/5.26 |
Elp4 | 0.76/1.09 | 0.25/1.12 | 5.62/0.30 | 1.29/1.37 | 1.03/1.21 | 14.19/5.74 | 10.08/6.88 |
Ext2 | 0.44/0.46 | 0.68/1.16 | 23.82/0.23 | 31.23/1.21 | 21.21/0.41 | 20.92/4.07 | 11.20/3.83 |
Fmnl2 | 0.18/1.37 | 0.15/0.44 | 11.91/9.50 | 5.60/0.20 | 12.75/1.80 | 15.11/1.84 | 21.28/23.52 |
Fubp3 | 0.04/0.99 | 0.42/1.88 | 14.72/5.69 | 34.28/34.4 | 32.79/41.90 | 93.41/11.27 | 73.83/20.93 |
Gapvd1 | 0.04/0.18 | 0.09/3.47 | 3.56/5.04 | 5.04/13.37 | 3.84/8.91 | 3.82/4.01 | 3.24/2.43 |
Gmeb2 | 0.30/1.39 | 0.70/0.70 | 15.73/5.58 | 17.11/1.21 | 7.65/0.98 | 2.14/13.63 | 2.63/9.73 |
Hat1 | 0.56/0.99 | 0.09/1.32 | 12.93/24.06 | 49.03/30.61 | 46.29/21.08 | 26.19/20.45 | 29.7/11.00 |
Il15ra | 1.42/0.59 | 0.07/0.54 | 2.25/11.67 | 0.64/5.29 | 2.21/12.29 | 4.80/14.33 | 1.58/20.32 |
Mapkbp1 | 0.03/0.18 | 0.13/2.25 | 96.09/4.23 | 25.15/33.87 | 22.48/30.68 | 123.55/25.01 | 263.85/15.93 |
Mga | 0.68/0.24 | 0.34/0.68 | 4.24/12.63 | 4.57/28.72 | 5.14/27.86 | 8.89/78.35 | 7.84/62.23 |
Mkks | 0.26/0.64 | 0.25/0.71 | 1.66/4.26 | 3.04/5.77 | 2.84/4.51 | 6.40/4.39 | 6.51/3.77 |
Mllt10 | 0.11/1.18 | 0.06/0.54 | 5.21/2.72 | 32.27/10.63 | 27.76/16.87 | 15.03/12.57 | 12.67/9.62 |
Mrps5 | 0.30/0.37 | 0.29/0.79 | 2.85/11.87 | 3.12/12.53 | 1.15/5.55 | 16.43/1.34 | 8.73/1.72 |
Necab3 | 3.74/0.72 | 0.49/0.20 | 3.72/10.21 | 2.23/38.12 | 6.28/36.48 | 11.85/20.21 | 3.01/23.07 |
Nr6a1 | 0.87/2.71 | 0.40/0.63 | 18.84/2.64 | 14.87/0.78 | 18.42/2.54 | 41.84/5.30 | 67.71/1.82 |
Ntng2 | 0.19/0.21 | 0.25/0.33 | 0.4/82.62 | 10.52/20.87 | 12.47/18.91 | 4.3/102.97 | 1.66/221.24 |
Nusap1 | 0.59/1.31 | 1.62/0.83 | 0.56/4.26 | 0.21/4.42 | 0.4/5.07 | 2.96/8.61 | 4.62/7.64 |
Olfr73 | 0.10/0.04 | 0.27/0.02 | 1.12/0.60 | 4.73/1.36 | 1.03/1.28 | 20.44/3.31 | 5.83/3.40 |
P2rx3 | 0.88/0.59 | 0.47/0.52 | 0.77/5.49 | 5.71/32.77 | 1.29/28.59 | 5.36/15.24 | 12.31/12.91 |
Pdhx | 1.09/0.82 | 0.10/0.80 | 11.01/2.93 | 7.06/3.08 | 5.76/1.16 | 5.97/16.23 | 6.61/8.67 |
Phf20 | 0.77/3.35 | 0.87/0.37 | 0.88/2.17 | 5.00/1.11 | 3.20/3.81 | 1.03/7.36 | 0.67/1.62 |
Polr3f | 0.83/1.25 | 0.21/0.69 | 10.77/16.44 | 10.86/12.56 | 14.35/15.82 | 15.73/35.52 | 7.5/57.87 |
Rae1 | 0.71/0.82 | 0.58/0.91 | 0.59/0.56 | 1.34/11.47 | 1.61/13.79 | 4.08/4.73 | 1.55/1.89 |
Rbm38 | 1.52/0.58 | 0.11/0.70 | 18.93/2.24 | 5.43/1.14 | 12.22/1.26 | 10.19/9.83 | 8.49/7.36 |
Scn1a | 9.47/0.74 | 2.38/0.87 | 0.73/1.13 | 0.61/3.84 | 2.46/3.60 | 7.56/0.30 | 4.58/0.57 |
Slc12a5 | 4.24/0.92 | 0.59/2.15 | 2.84/0.38 | 3.26/0.04 | 3.41/0.21 | 4.93/2.38 | 5.08/3.83 |
Slc27a4 | 1.12/0.22 | 0.50/0.41 | 28.79/0.72 | 13.26/3.52 | 6.48/0.62 | 6.51/15.87 | 6.71/4.40 |
Slc34a3 | 0.33/1.15 | 0.38/0.69 | 10.17/0.48 | 10.98/4.46 | 19.71/0.89 | 20.08/4.17 | 17.79/9.87 |
Spata2 | 0.54/1.15 | 0.59/0.13 | 0.65/8.00 | 1.75/4.87 | 0.78/3.99 | 4.44/4.06 | 3.95/4.56 |
Sptlc3 | 0.42/0.74 | 0.31/1.10 | 26.19/5.08 | 2.31/7.18 | 13.32/8.05 | 179.36/10.23 | 250.13/8.40 |
Ss18l1 | 0.33/1.71 | 1.15/1.85 | 24.07/1.10 | 70.3/5.51 | 106.73/3.61 | 142.18/1.19 | 87.02/0.81 |
Surf6 | 0.14/2.78 | 0.03/0.71 | 0.36/0.10 | 1.56/1.44 | 0.98/0.59 | 4.86/3.33 | 5.65/2.12 |
Timm10 | 1.11/0.80 | 0.16/0.19 | 0.79/7.50 | 0.44/7.32 | 0.44/9.91 | 3.52/10.71 | 2.82/4.98 |
Trub2 | 0.41/1.52 | 0.58/1.33 | 0.34/0.72 | 1.71/1.45 | 0.55/1.77 | 4.38/4.31 | 1.61/1.68 |
Ttll9 | 0.06/2.02 | 0.03/0.34 | 13.59/16.46 | 4.75/4.47 | 8.44/10.41 | 63.39/8.51 | 39.11/7.1 |
Yme1l1 | 1.17/14.07 | 0.17/3.87 | 4.23/0.82 | 10.71/0.64 | 12.14/2.59 | 21.28/7.73 | 18.6/4.72 |
Arl6ip6 | 0.33/5.28 | 0.27/0.91 | 0.09/2.37 | 1.77/2.62 | 1.30/2.81 | 3.37/4.03 | 2.27/4.19 |
Cep152 | 0.58/2.53 | 1.26/5.71 | 1.95/0.32 | 28.84/1.17 | 18.63/0.56 | 5.03/3.14 | 2.63/3.27 |
Chd6 | 0.54/0.90 | 1.20/0.97 | 11.69/10.67 | 70.65/11.16 | 61.55/20.31 | 58.35/20.35 | 34.4/18.12 |
Ddb2 | 3.10/1.00 | 0.72/1.06 | 10.74/0.56 | 81.94/1.53 | 91.16/0.66 | 88.59/3.99 | 61.48/3.57 |
Dnmt3b | 1.85/0.69 | 0.05/0.56 | 1.45/22.66 | 16.44/1.80 | 14.99/11.27 | 3.61/151.12 | 1.68/211.91 |
Dut | 0.04/2.30 | 0.36/0.50 | 0.80/1.54 | 2.32/5.41 | 1.35/3.55 | 14.44/1.97 | 9.05/1.33 |
Emilin3 | 0.83/0.44 | 0.86/0.29 | 26.92/0.25 | 42.07/1.28 | 59.95/0.79 | 7.44/4.22 | 12.92/4.95 |
Entpd6 | 1.61/1.68 | 0.30/0.48 | 41.36/0.66 | 38.04/0.30 | 17.21/0.32 | 17.79/3.07 | 12.23/2.46 |
Mettl5 | 0.61/0.10 | 0.37/0.06 | 2.72/10.00 | 6.88/3.21 | 4.9/6.00 | 6.01/46.04 | 5.83/28.46 |
Myef2 | 0.58/0.69 | 0.11/0.33 | 0.74/1.38 | 0.91/3.04 | 2.12/3.57 | 4.87/9.78 | 3.94/8.22 |
Rif1 | 0.94/1.19 | 1.76/3.64 | 0.98/14.02 | 5.85/10.48 | 7.01/7.97 | 3.27/6.11 | 2.11/0.65 |
Sfmbt2 | 2.56/2.25 | 3.80/1.98 | 1.09/1.49 | 7.35/0.88 | 9.00/1.40 | 2.16/7.25 | 0.94/5.39 |
(B) Genes down-regulated between 1-and 4-folds in TCs as compared with others | |||||||
Gzf1 | 1/3.12 | 3.24/1.05 | 17.78/47.88 | 13.78/42.76 | 10.39/19.69 | 8.17/20.02 | 1.12/13.88 |
Pltp | 9.94/3.83 | 2.17/3.01 | 189.9/16.60 | 7.67/31.99 | 8.30/21.33 | 110.19/13.79 | 96.66/22.44 |
Polr1b | 1.83/1.59 | 1.33/1.47 | 7.01/5.03 | 6.45/10.25 | 3.06/18.41 | 10.71/37.36 | 8.50/46.25 |
Tasp1 | 2.19/7.78 | 1.12/8.13 | 1.96/2.59 | 15.91/2.34 | 12.47/4.49 | 20.97/8.59 | 8.31/9.50 |
Zbtb34 | 2.82/4.42 | 1.78/2.60 | 58.06/2.67 | 131.6/19.40 | 78.44/15.48 | 69.44/25.45 | 58.72/10.27 |
Zfp120 | 1.92/1.70 | 1.84/1.62 | 17.79/11.67 | 21.29/13.60 | 18.08/11.68 | 11.75/7.33 | 8.68/5.36 |