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. 2014 Aug 27;15(1):99. doi: 10.1186/s12931-014-0099-9

Table 2.

Main differences between the population in which the 2008 score was developed and the present population. All p ≤ 0.001

Variable Present population 2008 population
Sex, % women 23.2 30.0
Age (years, mean ± SD ) 70.3 ± 11.3 72.5 ± 11.8
Smoking status, %
●Non smoker 6.6 19.3
●Ex smoker 60.8 49.9
●Smoker 32.6 30.8
MRC dyspnea grade at steady state, %
●0/1 17.1 22.5
●2-3 69.9 46.2
●4 13.0 31.3
Maintenance treatment, %
●LTOT 37.7 23.2
●Inhaled corticosteroids 72.4 43.8
●Oral corticosteroids 7.8 13.8
●Bronchodilators 86.6 69.6
Clinical signs of severity, %
●Cyanosis 22.1 29.0
●Use of accessory inspiratory muscles 27.9 50.9
●Paradoxical abdominal movement 8.6 36.8
●Asterixis 1.8 7.8
●Neurological impairment 6.9 11.8
●Lower limb edema 13.3 23.3
Number of clinical signs of severity, %
●None 44.1 27.6
●1 -2 45.9 47.7
● ≥ 3 10.0 24.7
Mortality (%) 2.5 7.9