Table 1. Values of K d and relative binding affinities of wild-type insulin and [GlnB22]-insulin.
K d±S.E. | Potencya | |
nM (n) | % | |
Wild-type insulin | 0.42±0.03 (3) | 100±7 |
[GlnB22]-insulin | 2.1±0.02 (4) | 19.9±0.2 |
Relative receptor binding affinity (potency) is defined as (Kd of human insulin/Kd of analogue) ×100.