Table 2. Correlation between plasma levels of MMP-11 and clinicopathological parameters in 330 OSCC patients.

	No. of case (%)	MMP-11 level	p value
Variables	n = 330	Mean ± S.D. (ng/mL)
Age (years)
<55	166 (50.3%)	15.69±10.12	0.592
≥55	164 (49.7%)	15.12±9.10
Smoking status
No	35 (10.6%)	14.08±9.44	0.388
Yes	295 (89.4%)	15.56±9.64
Drinking status
No	138 (41.8%)	14.85±9.45	0.377
Yes	192 (58.2%)	15.80±9.74
Betel nuts chewing
No	72 (21.8%)	14.36±9.51	0.297
Yes	258 (78.2%)	15.70±9.65
Cancer location
Buccal mucosa	120 (36.4%)	14.17±9.00	0.195
Tongue	98 (29.7%)	15.24±9.61
Gingiva	49 (14.8%)	16.60±10.88
Others	63 (19.1%)	17.10±9.61
Stage
I+II	131 (39.7%)	12.90±8.01	<0.001 *
III+IV	199 (60.3%)	17.06±10.23
Tumor T status
T1+T2	189 (57.3%)	13.85±8.64	0.001 *
T3+T4	141 (42.7%)	17.48±10.47
Lymph node status
N0	201 (60.9%)	14.25±8.98	0.006 *
N1+N2+N3	129 (39.1%)	17.21±10.32
Metastasis
M0	328 (99.4%)	15.31±9.56	0.183
M1	2 (0.6%)	30.86±6.65
Cell differentiation
Well differentiated	35 (10.6%)	15.36±9.38	0.975
Moderately or poorly differentiated	295 (89.4%)	15.41±9.66

*p<0.05.