Table 1. Characteristics of studies included in the meta-analysis.
Variants | First author | Year | Country | Ethnicity | Disease | Genotyping Methods | Case/Control | Quality score |
rs4132601 | Papaemmanuil* | 2009 | UK | Europeans | B-cell ALL | Illumina Infinium Human 370Duo BeadChips | 459/1438 | 11 |
(T>G) | Papaemmanuil# | 2009 | UK | Europeans | B-cell ALL | Illumina Infinium Human 370Duo BeadChips | 365/960 | 11 |
Lautner-Csorba | 2012 | Hungary | Europeans | B-cell ALL | Sequenom iPLEX Gold MassARRAY | 390/529 | 10 | |
Lin | 2014 | China | Asians | B-cell ALL | TaqMan | 45/80 | 6 | |
Prasad | 2010 | Germany | Europeans | B-cell ALL | Kaspar allele-specific PCR | 1193/1516 | 11 | |
Prasad | 2010 | UK | Europeans | B-cell ALL | Kaspar allele-specific PCR | 191/361 | 11 | |
Vijayakrishnan | 2010 | Thailand | Asians | B-cell ALL | Kaspar allele-specific PCR | 172/182 | 9 | |
Ellinghaus | 2012 | Germany | Europeans | B-cell ALL | SNPlex and TaqMan | 419/474 | 10 | |
Ellinghaus | 2012 | Germany | Europeans | B-cell ALL | SNPlex and TaqMan | 406/1682 | 10 | |
Ellinghaus | 2012 | Italy | Europeans | B-cell ALL | SNPlex and TaqMan | 287/579 | 10 | |
Healy | 2010 | Canada | Europeans | B-cell ALL | allele-specific primer extension | 284/270 | 8 | |
Oris | 2012 | France | Europeans | B-cell ALL | Human CNV370-Quad Illumina beadchip | 361/1542 | 9 | |
Papaemmanuil* | 2009 | UK | Europeans | T-cell ALL | Illumina Infinium Human 370Duo BeadChips | 44/1438 | 11 | |
Papaemmanuil# | 2009 | UK | Europeans | T-cell ALL | Illumina Infinium Human 370Duo BeadChips | 39/960 | 11 | |
Lautner-Csorba | 2012 | Hungary | Europeans | T-cell ALL | Sequenom iPLEX Gold MassARRAY | 78/529 | 10 | |
Lin | 2014 | China | Asians | T-cell ALL | TaqMan | 32/80 | 6 | |
Vijayakrishnan | 2010 | Thailand | Asians | T-cell ALL | Kaspar allele-specific PCR | 18/182 | 9 | |
Oris | 2012 | France | Europeans | T-cell ALL | Human CNV370-Quad Illumina beadchip | 41/1542 | 9 | |
Wang | 2013 | China | Asians | ALL | SNaPshot | 570/673 | 11 | |
Pastorczak | 2011 | Poland | Europeans | ALL | TaqMan | 398/731 | 10 | |
Rudant | 2013 | France | Europeans | AML | Illumina 370K Quad BeadChip | 51/414 | 9 | |
rs11978267 | Xu | 2013 | USA | Europeans | B-cell ALL | Affymetrix GeneChip | 574/2601 | 11 |
(A>G) | Xu | 2013 | USA | Africans | B-cell ALL | Affymetrix GeneChip | 128/1075 | 11 |
Xu | 2013 | USA | Europeans | B-cell ALL | Affymetrix GeneChip | 143/640 | 11 | |
Emerenciano | 2014 | Brasil | Mixed | B-cell ALL | Taqman | 77/490 | 9 | |
Emerenciano | 2014 | Brasil | Mixed | B-cell ALL | Taqman | 77/490 | 9 | |
Treviño | 2009 | USA | Europeans | B-cell ALL | Affymetrix 500K Array Set chips | 274/17958 | 10 | |
Healy | 2010 | Canada | Europeans | B-cell ALL | allele-specific primer extension | 284/270 | 8 | |
Ellinghaus | 2012 | Germany | Europeans | B-cell ALL | SNPlex and TaqMan | 419/474 | 10 | |
Ellinghaus | 2012 | Germany | Europeans | B-cell ALL | SNPlex and TaqMan | 406/1682 | 10 | |
Ellinghaus | 2012 | Italy | Europeans | B-cell ALL | SNPlex and TaqMan | 287/579 | 10 | |
Lautner-Csorba | 2012 | Hungary | Europeans | B-cell ALL | Sequenom iPLEX Gold MassARRAY | 390/529 | 10 | |
Linabery | 2013 | USA | Europeans | B-cell ALL | Taqman | 574/384 | 10 | |
Oris | 2012 | France | Europeans | B-cell ALL | Human CNV370-Quad Illumina beadchip | 361/1542 | 9 | |
Oris | 2012 | France | Europeans | T-cell ALL | Human CNV370-Quad Illumina beadchip | 41/1542 | 9 | |
Lautner-Csorba | 2012 | Hungary | Europeans | T-cell ALL | Sequenom iPLEX Gold MassARRAY | 78/529 | 10 | |
Linabery | 2013 | USA | Europeans | T-cell ALL | Taqman | 95/384 | 10 | |
Treviño | 2009 | USA | Europeans | T-cell ALL | Affymetrix 500K Array Set chips | 44/17958 | 10 | |
Ross | 2013 | USA | Europeans | ALL | Taqman | 96/384 | 9 | |
Ross | 2013 | USA | Europeans | AML | Taqman | 62/384 | 9 | |
Emerenciano | 2014 | Brasil | Mixed | AML | Taqman | 93/490 | 9 |
ALL: acute lymphoid leukemia; AML: acute myelogenous leukemia;
*: GWAS-1;
: GWAS-2.