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. 2014 Nov 25;9(11):e113748. doi: 10.1371/journal.pone.0113748

Table 1. Characteristics of studies included in the meta-analysis.

Variants First author Year Country Ethnicity Disease Genotyping Methods Case/Control Quality score
rs4132601 Papaemmanuil* 2009 UK Europeans B-cell ALL Illumina Infinium Human 370Duo BeadChips 459/1438 11
(T>G) Papaemmanuil# 2009 UK Europeans B-cell ALL Illumina Infinium Human 370Duo BeadChips 365/960 11
Lautner-Csorba 2012 Hungary Europeans B-cell ALL Sequenom iPLEX Gold MassARRAY 390/529 10
Lin 2014 China Asians B-cell ALL TaqMan 45/80 6
Prasad 2010 Germany Europeans B-cell ALL Kaspar allele-specific PCR 1193/1516 11
Prasad 2010 UK Europeans B-cell ALL Kaspar allele-specific PCR 191/361 11
Vijayakrishnan 2010 Thailand Asians B-cell ALL Kaspar allele-specific PCR 172/182 9
Ellinghaus 2012 Germany Europeans B-cell ALL SNPlex and TaqMan 419/474 10
Ellinghaus 2012 Germany Europeans B-cell ALL SNPlex and TaqMan 406/1682 10
Ellinghaus 2012 Italy Europeans B-cell ALL SNPlex and TaqMan 287/579 10
Healy 2010 Canada Europeans B-cell ALL allele-specific primer extension 284/270 8
Oris 2012 France Europeans B-cell ALL Human CNV370-Quad Illumina beadchip 361/1542 9
Papaemmanuil* 2009 UK Europeans T-cell ALL Illumina Infinium Human 370Duo BeadChips 44/1438 11
Papaemmanuil# 2009 UK Europeans T-cell ALL Illumina Infinium Human 370Duo BeadChips 39/960 11
Lautner-Csorba 2012 Hungary Europeans T-cell ALL Sequenom iPLEX Gold MassARRAY 78/529 10
Lin 2014 China Asians T-cell ALL TaqMan 32/80 6
Vijayakrishnan 2010 Thailand Asians T-cell ALL Kaspar allele-specific PCR 18/182 9
Oris 2012 France Europeans T-cell ALL Human CNV370-Quad Illumina beadchip 41/1542 9
Wang 2013 China Asians ALL SNaPshot 570/673 11
Pastorczak 2011 Poland Europeans ALL TaqMan 398/731 10
Rudant 2013 France Europeans AML Illumina 370K Quad BeadChip 51/414 9
rs11978267 Xu 2013 USA Europeans B-cell ALL Affymetrix GeneChip 574/2601 11
(A>G) Xu 2013 USA Africans B-cell ALL Affymetrix GeneChip 128/1075 11
Xu 2013 USA Europeans B-cell ALL Affymetrix GeneChip 143/640 11
Emerenciano 2014 Brasil Mixed B-cell ALL Taqman 77/490 9
Emerenciano 2014 Brasil Mixed B-cell ALL Taqman 77/490 9
Treviño 2009 USA Europeans B-cell ALL Affymetrix 500K Array Set chips 274/17958 10
Healy 2010 Canada Europeans B-cell ALL allele-specific primer extension 284/270 8
Ellinghaus 2012 Germany Europeans B-cell ALL SNPlex and TaqMan 419/474 10
Ellinghaus 2012 Germany Europeans B-cell ALL SNPlex and TaqMan 406/1682 10
Ellinghaus 2012 Italy Europeans B-cell ALL SNPlex and TaqMan 287/579 10
Lautner-Csorba 2012 Hungary Europeans B-cell ALL Sequenom iPLEX Gold MassARRAY 390/529 10
Linabery 2013 USA Europeans B-cell ALL Taqman 574/384 10
Oris 2012 France Europeans B-cell ALL Human CNV370-Quad Illumina beadchip 361/1542 9
Oris 2012 France Europeans T-cell ALL Human CNV370-Quad Illumina beadchip 41/1542 9
Lautner-Csorba 2012 Hungary Europeans T-cell ALL Sequenom iPLEX Gold MassARRAY 78/529 10
Linabery 2013 USA Europeans T-cell ALL Taqman 95/384 10
Treviño 2009 USA Europeans T-cell ALL Affymetrix 500K Array Set chips 44/17958 10
Ross 2013 USA Europeans ALL Taqman 96/384 9
Ross 2013 USA Europeans AML Taqman 62/384 9
Emerenciano 2014 Brasil Mixed AML Taqman 93/490 9

ALL: acute lymphoid leukemia; AML: acute myelogenous leukemia;

*: GWAS-1;

#

: GWAS-2.