Table 1. Baseline characteristics of the patients.
Characteristic | Total (n = 100) | Unfractionated heparin (n = 50) | Bivalirudin (n = 50) |
---|---|---|---|
Age (y), mean ± SD | 66.6 ± 12.3 | 64.9 ± 13.4 | 68.3 ± 10.9 |
Male gender, n (%) | 69 (69) | 30 (60)a | 39 (78)a |
Diabetes mellitus, n (%) | 87 (87) | 45 (90) | 42 (84) |
Hypertension, n (%) | 98 (98) | 49 (98) | 49 (98) |
Old myocardial infarction, n (%) | 37 (37) | 17 (34) | 20 (40) |
Left ventricle ejection fraction (%), mean ± SD | 56.7 ± 12.6 | 56.7 ± 13.5 | 56.7 ± 11.8 |
Old ischemic CVA, n (%) | 7 (7) | 5 (10) | 2 (4) |
Old hemorrhagic CVA, n (%) | 1 (1) | 1 (2) | 0 (0) |
Old GI bleeding, n (%) | 4 (4) | 4 (8) | 0 (0) |
Chronic renal failure, n (%) | 22 (22) | 9 (18) | 13 (26) |
Age >75 y, n (%) | 30 (30) | 16 (32) | 14 (28) |
Cr clearance < 60 mL/min, n (%) | 28 (28) | 14 (28) | 14 (28) |
9 mg% < Hb < 11 mg%, n (%) | 21 (21) | 11 (22) | 10 (20) |
Systemic BP > 180/95 mm Hg, n (%) | 58 (58) | 30 (60) | 28 (56) |
Steroid treatment, n (%) | 3 (3) | 1 (2) | 2 (4) |
Hematological problems, n (%) | 7 (7) | 2 (4) | 5 (10) |
NSTEMI on admission, n (%) | 32 (32) | 19 (38) | 13 (26) |
Abbreviations: BP, blood pressure; Cr, creatinin; CVA, cerebrovascular accident; GI, gastrointestinal; Hb, hemoglobin; NSTEMI, non-ST elevation myocardial infarction; SD, standard deviation.
p = 0.052.