Modulation across an ICC lamina. ICC recording sites from 12 animals and three different frequency ranges (low frequency, nshanks=29, nsites=86; middle frequency, nshanks=47, nsites=189; high frequency, nshanks= 44, nsites=158) were mapped onto their corresponding isofrequency plane. Modulated locations showed significant suppressive or facilitatory residual changes to PAES-18. Modulated and unmodulated locations were distributed throughout an entire ICC lamina.