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Correlation between p62 expression and F-actin ring formation during osteoclastogenesis. Immunofluorescence staining was performed to locate TRITC-conjugated p62 or LC3 and FITC-labeled F-actin ring. (A) During sRANKL-induced osteoclastogenesis, p62 expression is decreased (indicated by arrows) in the center of F-actin ring. (B) During sRANKL-induced osteoclastogenesis, the accumulation of LC3 was observed (indicated by arrows) in the center of F-actin ring. Scale, 50 µm.
