Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Dec;62(12):879–888. doi: 10.1369/0022155414551367

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2014

PMC Copyright notice

Figure 3. — Knockdown of p62 inhibits autophagy activation in osteoclasts induced by sRANKL. (A, B) Both the mRNA and protein expression levels of p62 were decreased in osteoclasts after treatment with p62 siRNA as compared with the negative control (NC). (C) Knockdown of p62 significantly decreased the mRNA expression levels of Atg5, Atg7, LC3 and Atg12 in sRANKL-treated osteoclasts. mRNA expression was normalized against β-actin in the samples analyzed. The data represent mean ± SEM from three different experiments performed in duplicate. *p<0.05; **p<0.01 versus the negative control.