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. 2014 Sep 25;13(6):1075–1085. doi: 10.1111/acel.12273

Figure 4.

Figure 4

DR increases movement and stress resistance independently of NAD+ salvage. (A,B) DR increased the rate of spontaneous movement comparably in aging WT and pnc-1(pk9605) animals. Body bends per minute were scored. Note that pnc-1 mutation did not affect the percentage increase associated with DR. (C,D) DR comparably increased thermotolerance (survival at 38 °C) in WT and pnc-1 animals. The time points indicated refer to days after hatching. Composites of all analyses are shown, with individual experimental data, mean, standard error, percent change, and statistical analysis presented in Table S21 (Fig.4A,B), and Table S22 (Fig.4C,D). *t-test vs. AL,P < 0.05; **t-test vs. AL,P < 0.001; $t-test vs. age 13, P < 0.01; @t-test vs. age 10, P < 0.065; #t-test vs. age 10, P < 0.025.