Disruption of UNC-68/RyR blocks enhanced regeneration of optogenetically stimulated neurons. A, Average 24 h ALM regeneration of photo-stimulated and control neurons in unc-68(e540), dantrolene-, and nemadipine-A-treated animals. *p < 0.05 (multiple comparison in one-way ANOVA using a Tukey adjustment). B, Percentage behavioral response to blue light stimulation for animals with the indicated conditions. Wild-type animals with NO ATR and animals treated with nemadipine-A responded significantly less than animals with ATR and DMSO ATR, respectively, compared through a logistic regression. **p < 0.001 (as indicated by brackets). More than 25 trials using >5 animals for each measurement.