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. 2014 Nov 26;4:336. doi: 10.3389/fonc.2014.00336

Table 4.

Acute toxicity SBRT in Cyberknife and non-robotic series.

GU grade 2 (%) GU grade 3 (%) GI grade 2 (%) GI grade 3 (%) Scheme
CYBERKNIFE
Aluwini et al. (2) 15 8 12 2 38 Gy/4 consecutive fx (SIB 44 Gy/4 fx in DIL)
Bolzicco et al. (3) 12 0 18 0 35 Gy/5 consecutive fx
Friedland et al. (4) 0.9 0.9 35–36 Gy/5 consecutive fx
Kang et al. (5) 13.6 0 9.1 0 32–36 Gy/4 consecutive fx
Katz et al. (6) 4–4.7 0 3.6–4 0 35–36.25 Gy/5 consecutive fx
Oliai et al. (7) 19 4 4 0 36.25–37.5 Gy/5 consecutive fx
NON-ROBOTIC SBRTa
Alongi et al. (13) 40 0 10 0 35 Gy/5 fx on alternate days
Boike et al. (14) 7–33 0 0–27 0 45–50 Gy/5 fx separated ≥36 h
Loblaw et al. (15) 19 1 10 0 35 Gy/5 fx once a week
Madsen et al. (16) 21 2 13 0 33.5 Gy/5 consecutive fx
Menkarios et al. (17) 31 5 14 0 45 Gy/9 fx once a week
Current study 22.7 0 20.4 0 43.84–45.20 Gy/8 fx on alternate days

aRadiotherapy technique: volumetric modulated arc therapy (13), step and shoot IMRT (1416), 3DCRT (17), helical tomotherapy (current study).

SIB, simultaneous integrated boost; DIL, dominant intraprostatic lesion.