Table 4.
Acute toxicity SBRT in Cyberknife and non-robotic series.
GU grade 2 (%) | GU grade 3 (%) | GI grade 2 (%) | GI grade 3 (%) | Scheme | |
---|---|---|---|---|---|
CYBERKNIFE | |||||
Aluwini et al. (2) | 15 | 8 | 12 | 2 | 38 Gy/4 consecutive fx (SIB 44 Gy/4 fx in DIL) |
Bolzicco et al. (3) | 12 | 0 | 18 | 0 | 35 Gy/5 consecutive fx |
Friedland et al. (4) | – | 0.9 | – | 0.9 | 35–36 Gy/5 consecutive fx |
Kang et al. (5) | 13.6 | 0 | 9.1 | 0 | 32–36 Gy/4 consecutive fx |
Katz et al. (6) | 4–4.7 | 0 | 3.6–4 | 0 | 35–36.25 Gy/5 consecutive fx |
Oliai et al. (7) | 19 | 4 | 4 | 0 | 36.25–37.5 Gy/5 consecutive fx |
NON-ROBOTIC SBRTa | |||||
Alongi et al. (13) | 40 | 0 | 10 | 0 | 35 Gy/5 fx on alternate days |
Boike et al. (14) | 7–33 | 0 | 0–27 | 0 | 45–50 Gy/5 fx separated ≥36 h |
Loblaw et al. (15) | 19 | 1 | 10 | 0 | 35 Gy/5 fx once a week |
Madsen et al. (16) | 21 | 2 | 13 | 0 | 33.5 Gy/5 consecutive fx |
Menkarios et al. (17) | 31 | 5 | 14 | 0 | 45 Gy/9 fx once a week |
Current study | 22.7 | 0 | 20.4 | 0 | 43.84–45.20 Gy/8 fx on alternate days |