TABLE 1.

K_i in nanomolar concentrations for each experimental compound versus the specific receptor indicated

	ALK2	ALK3	ALK4	ALK5	ALK6	BMPR2	TGFBR2	AMPK	VEGFR2
LDN	40.72	<5	1825	565	<1	3845	140.4	1122	214.7
DMH2	42.77	5.4	1407	2418	<1	3845	86.48	3527	2418
VU5350	1970	92.3	Not done	Inactive	895	1660	85.6	150	14.9
1LWY	32	10,800	Inactive	Inactive	9830	Inactive	Inactive	Inactive	19,700

BMPR2, bone morphogenetic protein receptor 2; TGFBR2, transforming growth factor β receptor 2; AMPK, adenosine monophosphate–activated protein kinase; VEGFR2, vascular endothelial growth factor receptor 2.