Figure 4.
Intermittent ethanol exposure during adolescence reduces expression of α4- and δ-containing GABAAR in the DRM and soluble membrane fractions prepared from the hippocampus of rats 26 days after the last alcohol dose. (A) Representative western blots of GABAAR α1, α4, α5, and δ subunits in the soluble and DRM fractions in control (CRTL) and alcohol exposed (AIE) rats. (B) Quantitation of western blots of GABAAR α1, α4, α5, and δ subunits in the soluble and DRM fractions from control (open bars) and alcohol exposed (shaded bars) rats (n = 6–8/fraction/group; *p = 0.014).